منابع مشابه
Philosophy of new drug discovery.
It is a great honor for me to have been chosen as the recipient of the Hoechst-Roussel Award. I fully realize that this award was presented to me on behalf of the antibiotic research group at the Kitasato Institute and of outside researchers who have worked so diligently with me in the discovery of new antibiotics and their practical applications. It gives me great pleasure to have this opportu...
متن کاملEthnobotany, Ethnopharmacology and Drug Discovery
This manuscript is a review of a number of ethnobotany and ethnopharmacology texts and papers in order to arrive at current understanding and scope of ethnobotany and ethnopharmacology. It includes either a brief definition of both fields and presenting some examples on them. Also it has a glimpse on the geographical coverage of research works throughout the world, important issue of prope...
متن کاملMacrocycles in new drug discovery
Over the past several years, the prevalence of biologically active macrocycles in medici nal chemistry literature has been increasing. Numerous recent review articles have dis cussed the role that macrocycles can play in medicinal chemistry, in particular looking beyond the established importance of natural product macrocycles in drug discovery [1–3]. Driggers et al. have argued that macrocyc...
متن کاملNew directions for drug discovery
Modern drug discovery demands an integrative approach, using many different technologies, but ultimately based on an understanding of the pathophysiology of the disease state to be treated. Targeting drugs at the main pathophysiological process is the key to success. This issue needs to be addressed with the multiple screening systems available, which can be used to find new leads.
متن کاملHuman-Yeast Hybrids: New Visions to Genetic Disorders and Drug Discovery
Yeast has been a very helpful organism for centuries, especially with respect to fermentation of sugars and production of bread. However, for an even longer time, yeast has been a distant relative of humans having diverged from a common ancestor, about one billion years ago. More than one third of the yeast genes have human counterparts, despite this evolutionary distance. Yeast and human ortho...
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ژورنال
عنوان ژورنال: Microbiological Reviews
سال: 1986
ISSN: 0146-0749
DOI: 10.1128/mr.50.3.259-279.1986